Medial Research Network
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About
Why use MRN?
MRN is the largest nursing provider in the clinical trials sector, with the widest global coverage and innovative tools to deliver its projects. We specialize in the   COMPLEX ; studies with large numbers of countries, studies where IMP needs to be delivered in the home, as well as those with challenging patient populations - specifically pediatric clinical trials and rare disease cli...
MRN Management Team
MRN’s board and management team is made up of highly experienced clinical trial professionals, all with 20+ years’ experience across many disciplines including nursing, project management, clinical operations and data management. All team members have medical, CRO or Sponsor backgrounds and understand the challenges faced in today’s trial environment; having faced th...
A Brief History of MRN
2016 marked MRN’s 10 year anniversary; since foundation the company has expanded from covering just the UK through to 40 countries worldwide, with over 20,000 home clinical trial visits for over 2,000 patients. MRN Site Nurse Support and Home Trial Support services have supported over 65 sponsors and 15 CROs across more than 170 clinical trials.
Community Based Trial Vision
MRN’s long term vision is to support the ability to run clinical trials fundamentally based in the community. A traditional site focused clinical trial model significantly reduces the numbers of patients available to participate in trials as their physicians are not taking part, whereas MRN’s community based model makes trials easier for patients to participate. In communit...
Vision and Values
Vision MRN aims to create services to provide a platform for mainstream implementation of community-based clinical trials by 2020, which are designed to speed up clinical trials and make them efficient, bringing drugs to the market quicker for our customers and patients who volunteer to take part in the trials we support. Values Teamwork At MRN, we all work together towards ou...
Contact
Request a Proposal
If you would like to learn more about how our services could assist with your clinical trial, please get in touch. Please feel free to send any additional information using the attachment option.
Home
Home
MRN specializes in the conduct of clinical trial visits in the patient’s home and supporting clinical trial sites with nursing resources.  At MRN we understand the complexities of today’s clinical trial environment and the burden this places on both patients and sites. Our nursing services are designed to ease these burdens, therefore accelerating patient recruitmen...
HomeTrialSupport
Home Trial Support Country Coverage
MRN support global clinical trials with site coordinators and nurses as well as home clinical trial nurse teams in all major research countries around the world; currently operating in over 39 countries, through our broad vendor network, we are constantly exploring and investigating new regions to enable our sponsors to reach their patient populations.   Can’t see t...
What is Home Trial Support?
Home Trial Support takes the clinical trial to the patient by conducting visits in the home. Using Home Trial Support reduces the number of visits to site and significantly lessens the burden on patients and their families. This ease of participation directly increases patient recruitment by 60% or more and typically maintains retention at over 95% . Performing a number of visits in the ho...
What are the Benefits of Home Trial Support?
Home Trial Support provides a number of benefits for sponsors and CROs, clinical research sites, and most of all, the patient. For the patient, their families and carers: Some of the biggest challenges of delivering a successful clinical study are identifying, recruiting and retaining patients. Developing a strategy that places the patient at the center of your clinical trial is vital fo...
How does MRN train its Nurses?
We only use nurses who have previous experience in conducting patient visits at home; these nurses are trained in the specific therapeutic area, the protocol and the study requirements, as well as ICH GCP. Training is conducted either at the beginning of the study, or as nurses are allocated to patients on a just in time basis.  Nurses only complete home visits once they have complete...
How does MRN Manage Home Visits?
Our Home Trial Support process ensures smooth running of homecare services, from consenting a patient to the service on site, through to the transfer of source data to site following the visit. Home Trial Support Process How is data reported to sponsors? Our nurses complete source documents (Visit Report Forms) in the patient’s home using electronic pens. All document...
Case histories
Overview text of case histories - to be provided.  
Case History 1 - Global
Indication: Neurology Countries: 12 countries  Sites: 88 sites in total / 84 used homecare Number of Patients: 972 / 797 used home trial support Total Number of Visits Conducted: Approximately 4,000 Situation: MRN was brought in to support a large international project spanning 12 countries, with a total of 88 sites and 972 patients randomized. The patients were on stud...
Case History 2 - Recruitment
Indication: Oncology Country: United Kingdom Sites: 6 sites in total / 5 used homecare Number of Patients: 63 Total Number of Visits Conducted: Over 3,200 across 2 years Situation: MRN’s Home Trial Support service was commissioned to support a complex oncology study requiring routine blood sampling for 63 patients across 6 sites in the UK including London, Midlands,...
Case History 3 - Retention
Indication: Oncology Country: United Kingdom  Sites: 3 sites in total Number of Patients: 57 Total Number of Visits Conducted: Over 2,200 across 3 years Situation: MRN’s Home Trial Support service was used in a long term complex study, which also required compounding within 24 hours of drug administration for 57 patients in 3 sites across the UK. Infusions ...
Making COMPLEX Trials Simple
MRN specializes in COMPLEX clinical trials. From studies in oncology, pediatrics or rare diseases, to IMP administration in the patients’ homes and global trials, our solutions are designed to make complex clinical trials simple to conduct. IMP Administration We are highly experienced in complex drug administration in the home. The IMP is carefully as...
How is Quality Maintained?
  MRN has developed a bespoke quality management system, MRN-COMPLY, that defines how the business is managed and how our trial activities are undertaken. MRN-COMPLY is made up of our unique document suite, including: ~20 Standard Operating Procedures (SOPs), ~100 guidelines, policies and ~200 templates, which have all been developed to ensure regulator...
Case History 1 - Global
Indication: Neurology Countries: 12 countries  Sites: 88 sites in total / 84 used homecare Number of Patients: 972 / 797 used home trial support Total Number of Visits Conducted: Approximately 4,000 Situation: MRN was brought in to support a large international project spanning 12 countries, with a total of 88 sites and 972 patients randomized. The patients were on stud...
Case History 2 - Recruitment
Indication: Oncology Country: United Kingdom Sites: 6 sites in total / 5 used homecare Number of Patients: 63 Total Number of Visits Conducted: Over 3,200 across 2 years Situation: MRN’s Home Trial Support service was commissioned to support a complex oncology study requiring routine blood sampling for 63 patients across 6 sites in the UK including London, Midlands,...
Case History 3 - Retention
Indication: Oncology Country: United Kingdom  Sites: 3 sites in total Number of Patients: 57 Total Number of Visits Conducted: Over 2,200 across 3 years Situation: MRN’s Home Trial Support service was used in a long term complex study, which also required compounding within 24 hours of drug administration for 57 patients in 3 sites across the UK. Infusions ...
legals
Terms and Conditions
Terms for Medical Research Network Web Site 1.    Use of Web Site All use of the web site www.themrn.co.uk (“the Site”) is on the Terms below (“the Terms”). By using the Site, you indicate that you accept and agree to abide by the Terms. If you do not agree to the Terms, please cease use of the Site immediately. You ...
News
OpenVacancies
Proposals and Contracts Administrator
Are you: • Looking for a new challenge? • Looking to join a dynamic, fast-growing organisation? • Looking to be a valued member of the team? If so, we have a unique opportunity for you ………… The Medical Research Network are a Clinical Trial Support Organisation looking to employ a Full Time Budgets, Proposals and...
Senior Project Manager
Are you: • Looking for a new challenge? • Looking to join a dynamic, fast-growing organisation? • Looking to be a valued member of the team? If so, we have a unique opportunity for you ………… The Medical Research Network are a Clinical Trial Support Organisation looking to employ a Full Time Project Manager for th...
SiteNurseSupport
What is Site Nurse Support?
Our Site Nurse Support service places experienced and trained research nurses and study site co-ordinators (SSCs) into sites to overcome resource constraints. Placements can be made at single sites, or nursing and project teams can be created to support multiple sites globally across a clinical trial. Our extensive network of professionals means we can provide resources to sites in over 37&nb...
Benefits of Site Nurse Support
Site Nurse Support provides a site-centric solution to patient recruitment and patient retention issues faced by Sponsors. Additional resources at sites help Sponsors identify and recruit patients faster as well as improve the quality of care provided to patients. Having experienced research nurses or study site co-ordinators onsite also enables trial naïve sites to participate in clinic...
How does MRN train its Nurses and Study Site Coordinators?
All our research nurses and co-ordinators are selected according to the individual visit, site or trial requirements. For example, where clinical sites have little or no clinical trial experience, we will ensure the individual placed is very experienced and can not only support the site, but also train and mentor staff on trial requirements. All our nurses are fully trained in ICH GCP...
Case Histories
Overview text of case histories - to be provided.
Case History 1 - Trial Naive
Indication: Rheumatoid Arthritis Country: United Kingdom Sites: 34 sites in total / 14 used Site Nurse Support Situation: MRN was involved in selecting and setting up 34 sites within the UK for a late phase rheumatoid arthritis study, the remit being to identify and utilize a wide spread site base, covering all geographical regions and reaching into trial naive sites, where required...
Case History 2 - Patient ID
RESCUE STUDY Indication: Cardiology Country: United Kingdom Sites : 10 sites The cardiology study was failing to recruit due to: • Complex inclusion and exclusion criteria • Limited on site staff to conduct database searches MRN provided a team of 5 research nurses to conduct database searches across 10 sites, over a 12 month period. Sites had identified approximate...
Case History 3 - Global Support
Indication: Neurology (Parkinson’s Disease) Countries: 9 Countries (United Kingdom, Belgium, Netherlands, Poland, Germany, Thailand, Spain, Australia and Portugal) Sites: 20 MRN provided a team of multi lingual neurology specialist nurses across 9 countries. Nurses were required to sites with 24 hours’ notice. Patients were titrated via a jejunal tube over 10 days for...
How Does MRN Manage its Site Visits?
For every trial adopting Site Nurse Support a Project Manager (PM) and a Nurse Manager (NM) are assigned. The Project Manager is responsible for the set up and conduct of the services across all countries; based at our head office in the UK or our North American office, the Project Manager is the primary point of contact for the Sponsor and/or CRO team. All activities and visits are tracked, s...
Case History 1 - Trial Naive
Indication: Rheumatoid Arthritis Country: United Kingdom Sites: 34 sites in total / 14 used Site Nurse Support Situation: MRN was involved in selecting and setting up 34 sites within the UK for a late phase rheumatoid arthritis study, the remit being to identify and utilize a wide spread site base, covering all geographical regions and reaching into trial naive sites, where required...
Case History 2 - Patient ID
RESCUE STUDY Indication: Cardiology Country: United Kingdom Sites : 10 sites The cardiology study was failing to recruit due to: • Complex inclusion and exclusion criteria • Limited on site staff to conduct database searches MRN provided a team of 5 research nurses to conduct database searches across 10 sites, over a 12 month period. Sites had identified approximate...
Case History 3 - Global Support
Indication: Neurology (Parkinson’s Disease) Countries: 9 Countries (United Kingdom, Belgium, Netherlands, Poland, Germany, Thailand, Spain, Australia and Portugal) Sites: 20 MRN provided a team of multi lingual neurology specialist nurses across 9 countries. Nurses were required to sites with 24 hours’ notice. Patients were titrated via a jejunal tube over 10 days for...
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